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Folfox Chemotherapy For Colorectal Cancer

By: Dr. Alina Home | Cancer | Colon-Cancer


Colorectal cancer occurs when the cells in the intestine mutate and it starts to grow uncontrollably. This results in the formation of tumors. Folfox is the combination chemotherapy treatment used for treating colorectal cancer.

In this treatment, a combination of different drugs such as Oxaliplatin (OX), Folinic Acid (FOL) and Fluorouracil (F) are used. This treatment helps to stop the growth of cancerous cells in the body. This treatment is usually given to the patients in stage three or four of colorectal cancer.

Chemotherapy treatment is given in stage four of colorectal cancer to prevent the symptoms from reoccurring or to provide relief. This cancer chemotherapy treatment is given in form of cycle. Each treatment cycle is for duration of two weeks.

This treatment is given by a health care professional or doctor by injecting it into the vein or given by mouth. They will also decide the dose and treatment to be administered to a patient. The factors that determine the dosage are your overall health, height and weight.

The side effects of this treatment can be increased or decreased and its severity can be changed. It depends on the combination of chemotherapy drugs used for treatment. These side effects may also sometimes take more than six months to recover after the completion of treatment. Everyone will not experience the same side effects. It is also dependent on the factors such as the treatment, dosage and your health.

You can consult a doctor and opt for the medicines prescribed by them which will give you a relief from the side effects.

The side effects of folfox chemotherapy are described below:

  • Fatigue

  • Increased risk of getting viral or bacterial infection

  • Breathlessness

  • Tiredness

  • Diarrhea

  • Nausea

  • Mouth ulcers


There are some very rare cases, where high temperature is a side effect seen in patients undergoing this treatment.

Many research studies have been conducted for developing advanced treatments for cancer and also deal with the side effects of the treatment. However, the information provided here will give you details about the folfox chemotherapy for colorectal cancer and its side effects.



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