Vitamin B12 has a long history and a solid reputation as an energy booster, and it is among the most important of all the B-complex vitamins. Vitamin B12 deficiency may result negative in hematological, neurological, and gastrointestinal conditions. Gastrointestinal effects of B12 deficiency may include diarrhea, constipation, abdominal pain, excessive flatulence, and a burning sensation on the tongue. Vitamin B12, a member of the B-vitamin family, is a term used collectively to represent a group of cobalt-containing compounds known as corrinoids. The principal cobalamins are cyanocobalamin, hydroxocobalamin, and the two coenzyme forms of vitamin B12, methylcobalamin, and 5-deoxyadenosylcobalamin (adenosylcobalamin). However, the term vitamin B12 is usually used to refer to only one of these forms, cyanocobalamin, which is used to fortify foods and nutritional supplements. Vitamin B12 is a water-soluble vitamin required for normal cell activity, DNA replication, and the synthesis of the mood-influencing substance SAMe. Vitamin B12, also known as cobalamin, works with folic acid to produce healthy red blood cells. Vitamin B12 also keeps your central nervous system healthy. Vitamin B12 helps maintain the myelin sheath that insulates nerve fibres from each other. B12 deficiency can cause a type of anemia marked by fewer but larger red blood cells that's called pernicious anemia. It can also cause walking and balance problems, sore tongue, weakness, confusion and, in advanced cases, dementia. Vegetarians who eliminate all animal sources from their diet (also known as vegans) may benefit from taking a vitamin B12 supplement. Vitamin B12 is bound to the protein in food. Hydrochloric acid in the stomach releases B12 from proteins in foods during digestion. Hydroxocobalamin is a man-made form of vitamin B12. Vitamin B12's main functions are in the formation of red blood cells and the maintenence of a healthy nervous system. Prolonged B12 deficiency can lead to nerve degeneration and irreversible neurological damage. People with vitamin B12 deficiency show irregular destruction of the myelin sheaths, which eventually causes paralysis and death.Vitamin B12 levels decrease with age and various measures of cognitive impairment are associated with reduced B12 status. Vitamin B12 deficiencies occur when the body is unable to properly use the vitamin. Benifits Vitamin B12 Tips 1. Vitamin B12 are critical to the health of the nervous system and to a process that clears homocysteine from the blood. 2. Vitamin B12 is found naturally in food sources (principally animal products) in protein-bound forms. 3. Vitamin B12 deficiency can be a factor in a variety of different health conditions and disorders. 4. Vitamin B12 may help restrain pre-cancerous lung conditions in smokers. 5. Patients with Alzheimer's show low levels of Vitamin B12. 6.3 Vitamin B 12 and folate are required for the synthesis of S-adenosylmethionine, a methyl group donor essential for the metabolism of neurotransmitters. 7. Vitamin B12 deficiency can be a factor in a variety of different health conditions and disorders. 8. Vitamin B12 has been suggested to help defend against hypersensitivity to sulfites.
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