Acne Vulgaris (also known as acne) is a common skin condition that affects around 55 of people in the U.S in their lifetimes. Out of those people 20% of them will have severe acne which can scar them physically and mentally. Acne Vulgaris is the most common disease in the U.S and is known noninflammatory, closed or open comedowns, inflammatory papules, pustules, and nodules. The disease affects areas that have the densest amount of sebaceous follicles (oil glands) which are the face, back, and the upper part of the chest. The causes of acne vulgaris come from 4 factors which the first is genetics. For example if both parents had acne then most likely 3 out of 4 of their children will have acne. For some families though this skin condition skips generations which is similar to other genetic conditions. What the children inherit from their parents is the higher chance of their sebaceous follicles being clogged which will lead to the skin condition. Other things that could be gotten from parents are inflammation, excess sebum, and the activity of P. (Propionibacterium) acnes. Another of the main things that can trigger acne vulgaris is androgen hormones. These are hormones that are released ovaries, testis, and adrenal glands. Testosterone which is one of these hormones causes sebaceous follicle activity. Also androgen hormones receptors are found within sebaceous glands and if the receptors malfunction they do not cultivate acne. A third cause of acne vulgaris is an excess of sebum. Sebum is dictated by different mediators and hormones. A main factor in causing an excess in sebum is androgen hormones but even though it is most men and women who have acne vulgaris have a normal circulation of androgen hormones. Some other things that control sebum are growth hormones and insulin like growth factors.
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